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2022 Winter Simulation Conference, WSC 2022 ; 2022-December:1223-1234, 2022.
Article in English | Scopus | ID: covidwho-2249506

ABSTRACT

Pandemics have huge impact on all aspect of people's lives. As we have experienced during the Coronavirus pandemic, healthcare, education and the economy have been put under extreme strain. It is important therefore to be able to respond to such events fast in order to limit the damage to the society. Decision-makers typically are advised by experts in order to inform their response strategies. One of the tools that is widely used to support evidence-based decisions is modeling and simulation. In this paper, we present a hybrid agent-based and discrete-event simulation for the Coronavirus pandemic management at regional level. Our model considers disease dynamics, population interactions and dynamic ICU bed capacity management and predicts the impact of various public health preventive measures on the population and the healthcare service. © 2022 IEEE.

2.
Philos Trans A Math Phys Eng Sci ; 379(2197): 20200221, 2021 May 17.
Article in English | MEDLINE | ID: covidwho-1155842

ABSTRACT

We present the VECMA toolkit (VECMAtk), a flexible software environment for single and multiscale simulations that introduces directly applicable and reusable procedures for verification, validation (V&V), sensitivity analysis (SA) and uncertainty quantication (UQ). It enables users to verify key aspects of their applications, systematically compare and validate the simulation outputs against observational or benchmark data, and run simulations conveniently on any platform from the desktop to current multi-petascale computers. In this sequel to our paper on VECMAtk which we presented last year [1] we focus on a range of functional and performance improvements that we have introduced, cover newly introduced components, and applications examples from seven different domains such as conflict modelling and environmental sciences. We also present several implemented patterns for UQ/SA and V&V, and guide the reader through one example concerning COVID-19 modelling in detail. This article is part of the theme issue 'Reliability and reproducibility in computational science: implementing verification, validation and uncertainty quantification in silico'.

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